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项目介绍 2023年05月24日 13:27 125 im

  

Introduction

  With the advancement of technology, the study of stem cells has become a hot topic in the medical industry. Stem cells are undifferentiated cells that can develop into various types of cells under specific conditions, such as cells for organs and tissues in our bodies. They have the potential to be used for cell therapy or tissue engineering, which can help treat diseases and injuries.

  Japan is known for being one of the top countries in stem cell research and development. Japanese scientists have made significant contributions in the field of stem cell therapies. In this article, we will focus on some of the famous Japanese stem cell brands and their research.

  

1. RIKEN Center for Developmental Biology

  RIKEN Center for Developmental Biology was established in 2000 and is located in Kobe, Japan. They specialize in research on embryonic stem cells and induced pluripotent stem (iPS) cells, which are somatic cells that have been reprogrammed to have stem cell-like properties. Their research focuses on the development of tissues and organs, as well as understanding the mechanisms of development.

  One groundbreaking research project conducted by RIKENs team led by Dr. Shinya Yamanaka is the creation of iPS cells, which earned him a Nobel Prize in Physiology or Medicine in 2012. This discovery revolutionized the field of stem cell research, as it eliminates the need to use embryonic stem cells, which raises ethical concerns.

  

2. StemRIM Co., Ltd.

  StemRIM Co., Ltd. is a Japanese biotech company that specializes in regenerative medicine using iPS cells. Their main focus is on developing treatments for age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly. They are conducting clinical trials for a treatment that involves transplanting retinal pigment epithelial cells derived from iPS cells into patients with AMD.

  Their technology is based on the research conducted by Professor Masayo Takahashi of the RIKEN Center for Developmental Biology, who led the first clinical trial of a stem cell-based therapy in Japan in 2014. The trial involved the transplantation of retinal pigment epithelial cells derived from iPS cells into a patient with AMD, which showed promising results.

  

3. ReproCELL Inc.

  ReproCELL Inc. is a Japanese biotech company that focuses on producing and distributing human stem cells and related products for research and drug discovery. They offer a wide range of products, including iPS cells, neural cells, cardiac cells, and hepatocytes.

  One of their notable products is the Human iPS Cell-Derived Neural Stem Cell Kit, which allows researchers to culture and differentiate neural stem cells derived from iPS cells. This kit is used for various applications, such as studying neural development and modeling diseases like Alzheimers and Parkinsons.

  

4. Cyfuse Biomedical K.K.

  Cyfuse Biomedical K.K. is a Japanese company that specializes in the development of tissue engineering technology using iPS cells. Their technology, called "Regenova," allows for the fabrication of 3D tissues that can be used for transplantation or drug screening.

  Their research includes the development of liver tissues for drug toxicity screening, pancreatic tissues for diabetes treatment, and heart tissues for cardiac disease treatment. They are also developing an automated system for the production of 3D tissues, which will increase the efficiency of tissue engineering.

  

Conclusion

  Japan has made significant contributions to the field of stem cell research, and its brands have become leaders in the industry. The development of iPS cells has revolutionized stem cell research, and their potential for treating diseases is becoming more apparent. The future of regenerative medicine looks bright, and we can look forward to more groundbreaking discoveries and developments from Japan in this field.

标签: Regenova

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